There had been no long time facet effects proven as a result in taking -Keto. In the whole lot I have read, and those that I have talked to, both males and females, the recommended each day dosage is ,mg x each day. The next supplement is CLA (Conjugated Linoleic Acid). CLA is a naturally occurring discovered in animal and dairy fat consisting of red meat, dairy food, fowl, eggs and corn oil.